Jacob Bush is currently a group leader in the Chemical Biology department at GSK. He is a chemist by training with a PhD in chemical biology from Chris Schofield’s lab. With a burning interest for translational science he joined GSK in 2015 to explore ways to accelerate drug discovery. By combining chemoproteomic and chemogenomic approaches using covalent fragments, Jake and his team aim to discover new targets with therapeutic potential in addition to using machine learning algorithms to accelerate the drug discovery process.